Zoloft Weight Loss - Complete Detail About its Side Effects, Symptoms and Dosage

Are you looking detail at how to lose weight fast? Want to know about weight loss with Zoloft? or Interested to get information about Zoloft headache? If you are eager to get an answer to such questions, Here, we provided complete details about it. First, we have given detail about Zoloft drugs and then given detail about how to use it for weight loss and after that, you get information about its side effects and dosage at end of post.

What Is Zoloft?

Zoloft, generically known as sertraline, belongs to a category of antidepressants known as Selective Serotonin Reuptake Inhibitors, or SSRIs. Doctors prescribe Zoloft for treatment of depressive disorders, anxiety and other mental health conditions. Like other SSRIs, Zoloft may cause weight changes in some people. Knowing that this complication could occur can help you make necessary lifestyle adjustments to prevent it or deal with it effectively if you experience either one.

SSRIs are the most prescribed type of antidepressants in the United States today because they are thought to have fewer side effects than other types of antidepressants

Zoloft was originally developed for the United Kingdom market by Pfizer in 1990. It was released under the brand name Lustral and marketed as a safer alternative with fewer side effects and withdrawal symptoms than competing drugs like Prozac.

The Food and Drug Administration (FDA) approved Zoloft in 1999. By 2005, it was reportedly the most popular antidepressant on the U.S. market and the sixth most prescribed brand-name prescription medication, grossing nearly $ 2.6 billion.

In addition to treating major depressive disorders, which affect nearly 7 percent of adults in the United States, Zoloft is given to those suffering from post-traumatic stress disorder (PTSD), premenstrual dysphoric, and obsessive-compulsive disorder (OCD), along with generalized anxiety disorder (GAD), and panic disorder.

A proposed defective drug class-action lawsuit against Zoloft was thrown out by a federal judge in California due to the statute of limitations issues and other concerns. The California suit alleged the drug offers little more efficacy than a placebo and argued that Pfizer purposely omitted from Zoloft labeling any studies that showed Zoloft to be ineffective.

In dismissing the complaint, the judge did leave open the possibility that the suit could be revived after it's amended.
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Zoloft weight loss:

Weight loss is a common side effect of Zoloft but in most cases, it is not a serious concern. In children and adolescents, weight loss due to Zoloft is much more common and can become a very serious problem.

Weight Loss in Adults Taking Zoloft

In adults, weight loss due to Zoloft is usually only a pound or two when the treatment begins. Most patients report regaining the minuscule amount of weight after six months, or so, of treatment.
Some adults reported losing more significant amounts of weight, but that is a rare situation. In these rare cases, the patients had to stop taking Zoloft to keep from losing unhealthy amounts of weight. It is unclear why Zoloft causes this weight loss but some doctors believe Zoloft may affect the metabolism.

Weight Loss in Adolescents and Children

Dangerous weight loss in adolescents and children taking Zoloft is much more prevalent than in adults. Most children lose one pound when they first start Zoloft. In some cases, children continued to lose weight. Seven percent of children taking Zoloft lost more than seven percent of their total body weight.
In young children, this can be very dangerous. In adolescents, two percent experienced weight loss of more than seven percent of their total body weight. In most cases, the children and adolescents regained the weight after six to nine months of treatment.

Signs and Symptoms

Weight loss is often preceded by appetite loss, nausea upon eating, and disinterest in food preparation and consumption. Reduced caloric intake and occasionally an increase in physical activity because of reduced depressive symptoms are usually the primary causes of weight loss in patients taking Zoloft. Increased appetite, binge eating, food cravings and preoccupation with food are commonly associated with weight gain in people who take Zoloft. Poor dietary choices, such as eating foods high in saturated fats and sugars, are a major cause of weight gain for many people.


Weight changes of 5 to 10 pounds are unlikely to cause serious health problems for most people. However, rapid weight gain or loss can have health implications. Underweight people are more likely to suffer from reduced immunity, low energy levels, and nutritional deficiencies, the British National Health Services cautions. Underweight women may have irregular menstrual cycles and reduced fertility. Overweight issues and obesity are endemic in the United States. The National Heart Lung and Blood Institute states that overweight people are at an increased risk for heart disease, type II diabetes, sleep apnea and several types of cancer.


The best way to prevent excessive weight gain or weight loss while taking Zoloft is to adhere to a healthy diet and exercise regularly. Fresh fruits and vegetables, whole grains, lean meat and low-fat dairy products are excellent choices for a healthy diet. Strength-training exercises may help build muscle mass in underweight patients, while regular aerobic exercise like running or cycling can help burn calories in those who are overweight.

Side Effects of Zoloft:

Zoloft can cause more serious side effects in some patients. These may include:
  • Decreased interest in sex
  • Decrease in sexual ability
  • Muscle cramps/weakness
  • Bruising or bleeding easily
  • Shaking/tremor
  • Unusual weight loss
Seek help right away if you notice that your stool is black or bloody or if your vomit looks like coffee grounds.

On occasion, taking Zoloft leads to a very serious condition called serotonin syndrome, which requires emergency help. The risk of developing serotonin syndrome is greater if you are also taking other medications that increase serotonin.

The symptoms range from fast heartbeat, hallucinations, loss of coordination, and severe dizziness to twitching muscles, unexplained fever, nausea, vomiting, diarrhea, and unusual agitation or restlessness. Other rare problems include a painful or prolonged erection (priapism) for four hours or more. If this happens, you must get medical attention right away or permanent problems could result.

Serious allergic reactions are also rare but in the event, this occurs seek emergency assistance right away. The symptoms may include a rash, itching, or swelling particularly of the face, tongue, or throat as well as severe dizziness and trouble breathing.
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Make sure before using Zoloft:

You should not use Zoloft if you are allergic to sertraline, or if you also take pimozide. Do not use the liquid form of Zoloft if you are taking disulfiram (Antabuse) or you could have a severe reaction to the disulfiram.

Do not take Zoloft within 14 days before or 14 days after you take an MAO inhibitor. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

To make sure Zoloft is safe for you, tell your doctor if you have ever had:
  • heart disease, high blood pressure, or a stroke;
  • liver or kidney disease;
  • a seizure;
  • bleeding problems, or if you take warfarin (Coumadin, Jantoven);
  • bipolar disorder (manic depression); or
  • low levels of sodium in your blood.
Some medicines can interact with sertraline and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, other antidepressants, or medicine for mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Taking an SSRI antidepressant during pregnancy may cause serious lung problems or other complications in the baby. However, you may have a relapse of depression if you stop taking your antidepressant. Tell your doctor right away if you become pregnant. Do not start or stop taking Zoloft during pregnancy without your doctor's advice. It is not known whether sertraline passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Do not give Zoloft to anyone younger than 18 years old without the advice of a doctor. Zoloft is FDA-approved for children with obsessive-compulsive disorder (OCD). It is not approved for treating depression in children.
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Zoloft Dosage

Your dosage will be different depending on what condition you are treating and your age.

  • Major depressive disorder/obsessive-compulsive disorder: Take 50 mg once a day
  • Panic disorder, posttraumatic stress disorder (PTSD), and social anxiety disorder: Begin with one 25 mg dose daily. After you are using the drug for one week, the dose should be increased to 50 mg per day.
  • Premenstrual dysphoric disorder: Take one 50 mg per day, either daily throughout the menstrual cycle or during the latter phase of the menstrual cycle based on your doctor's recommendation.
Children and Adolescents:
  • Obsessive-compulsive disorder: Begin with 25 mg once a day in children between 6 and 12 years of age; in those between 13 and 17 start with 50 mg a day.
Depending upon its effect, your doctor may adjust the dosage. Never take it upon yourself to do so. You can take the medicine with or without food, in the morning or the evening. Try to take it at the same time each day so you don't forget.

If you are using the liquid form it must be diluted before you take it. It's a good idea to measure the medication with the dropper provided. You can mix it with four ounces of water, ginger ale, lemon/lime soda, lemonade, or orange juice. Do not use anything other than the liquids listed and be sure to drink the entire glass.

When you're done, refill the glass with water and drink it down to make sure you get all of the medicine.

Zoloft Overdose

Signs of an overdose may include tremor, agitation, vomiting, extreme drowsiness, and rapid heart rate. If you are having these symptoms and think you have taken too much Zoloft, call a poison help line at 1-800-222-1222 or get emergency medical help right away.

Missed Dose of Zoloft

If you forget to take Zoloft, take your missed medicine as soon as you remember unless it's almost time for your next dose.

Never take extra Zoloft to make up for a missed dose.
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